Rubina Kousar, Muhammad Naeem, Mohamad Ikhwan Jamaludin, Ammara Arshad, Aisyah Nazirah Shamsuri, Nelofar Ansari, Samreen Akhtar, Abu Hazafa, Jalal Uddin, Ajmal Khan, Ahmed Al-Harrasi: Exploring the anticancer activities of novel bioactive compounds derived from endophytic fungi: mechanisms of action, current challenges and future perspectives. Am J Cancer Res 2022;12(7):2897-2919. (Full text, PDF)
Muhammad Tufail, Jia Cui, Changxin Wu: Breast cancer: molecular mechanisms of underlying resistance and therapeutic approaches. Am J Cancer Res 2022;12(7):2920-2949. (Full text, PDF)
Susan Bal, Shaji K Kumar, Rafael Fonseca, Francesca Gay, Vania TM Hungria, Ahmet Dogan, Luciano J Costa: Multiple myeloma with t(11;14): unique biology and evolving landscape. Am J Cancer Res 2022;12(7):2950-2965. (Full text, PDF)
Dan Li, Xiaoli Liu, Ni Jiang, Di Ke, Qiang Guo, Kui Zhai, Hao Han, Xue Xiao, Tengyang Fan: Interfering with ITGB1-DT expression delays cancer progression and promotes cell sensitivity of NSCLC to cisplatin by inhibiting the MAPK/ERK pathway. Am J Cancer Res 2022;12(7):2966-2988. (Full text, PDF)
Tao Zhang, Jian Gu, Xinyi Wang, Jiajia Luo, Jing Yan, Kailin Cai, Huili Li, Yingli Nie, Xiangdong Chen, Jiliang Wang: RNA methylation regulators contribute to poor prognosis of hepatocellular carcinoma associated with the suppression of bile acid metabolism: a multi-omics analysis. Am J Cancer Res 2022;12(7):2989-3013. (Full text, PDF, Tables S1, S2, S3)
Mourad Zerfaoui, Koji Tsumagari, Eman Toraih, Youssef Errami, Emmanuelle Ruiz, Mohammed Sohail M Elaasar, Moroz Krzysztof, Andrew B Sholl, Sameh Magdeldin, Mohamed Soudy, Zakaria Y Abd Elmageed, A Hamid Boulares, Emad Kandil: Nuclear interaction of Arp2/3 complex and BRAFV600E promotes aggressive behavior and vemurafenib resistance of thyroid cancer. Am J Cancer Res 2022;12(7):3014-3033. (Full text, PDF)
Chenglong He, Liping He, Qiaowei Lu, Jianjun Xiao, Wenjing Dong: The functions and prognostic values of chemokine and chemokine receptors in gastric cancer. Am J Cancer Res 2022;12(7):3034-3050. (Full text, PDF)
Lu Li, Qing He, Zhenchao Tao, Rui Zhang, Yayun Cui, Liting Qian: Constructing novel molecular subtypes and an 11-gene signature based on pyroptosis signaling for lung adenocarcinoma. Am J Cancer Res 2022;12(7):3051-3066. (Full text, PDF)
Wei-Pang Chung, Wei-Lun Huang, Chun-Hui Lee, Hui-Ping Hsu, Wan-Ling Huang, You-Yu Liu, Wu-Chou Su: PI3K inhibitors in trastuzumab-resistant HER2-positive breast cancer cells with PI3K pathway alterations. Am J Cancer Res 2022;12(7):3067-3082. (Full text, PDF)
Beom Seok Han, Kyung Hee Jung, Ji Eun Lee, Young-Chan Yoon, Soyeon Ko, Min Seok Park, Yun Ji Lee, Sang Eun Kim, Ye Jin Cho, Pureunchowon Lee, Joo Han Lim, Eunsoo Jang, Hyunzu Kim, Soon-Sun Hong: Lidocaine enhances the efficacy of palbociclib in triple-negative breast cancer. Am J Cancer Res 2022;12(7):3083-3098. (Full text, PDF)
Leonid Cherkassky, Masanori Oshi, Eihab Abdelfatah, Rongrong Wu, Yamato Takabe, Li Yan, Itaru Endo, Kazuaki Takabe: An immune-inflamed tumor microenvironment as defined by CD8 score is associated with favorable oncologic outcomes in hepatocellular carcinoma independent of measures of tumor mutational burden. Am J Cancer Res 2022;12(7):3099-3110. (Full text, PDF)
Yali Gao, Xiaona Chen, Jun Zhang: LncRNA MEG3 inhibits retinoblastoma invasion and metastasis by inducing β-catenin degradation. Am J Cancer Res 2022;12(7):3111-3127. (Full text, PDF)
Rong-Qiang Yuan, Hui Zhao, Yan Wang, Kai Song, Jia Yang, Wei He, Da-Zhuang Miao, Qi Wang, Yun-He Jia: SEPTIN9-SDC2-VIM methylation signature as a biomarker for the early diagnosis of colorectal cancer. Am J Cancer Res 2022;12(7):3128-3140. (Full text, PDF)
Christopher Larson, Bryan Oronsky, Tony Reid: AdAPT-001, an oncolytic adenovirus armed with a TGF-β trap, overcomes in vivo resistance to PD-L1-immunotherapy. Am J Cancer Res 2022;12(7):3141-3147. (Full text, PDF)
Fang-Hai Han, Sheng-Ning Zhou, Guang-Yu Zhong, Jia-Nan Tan, Jing Huang, Han Gao, Zhi-Tao Chen, Jian-Kun Zhu, Shi-Lin Zhi, Jin-Tao Zeng, Bin Yang: Three-dimensional versus two-dimensional laparoscopic surgery for rectal cancer: better promote postoperative sexual and urinary function of a propensity-matched study. Am J Cancer Res 2022;12(7):3148-3163. (Full text, PDF)
Hung-Wei Wang, Pei-Chein Tsai, Chi-Yi Chen, Kuo-Chih Tseng, Hsueh-Chou Lai, Hsing-Tao Kuo, Chao-Hung Hung, Shui-Yi Tung, Jing-Houng Wang, Jyh-Jou Chen, Pei-Lun Lee, Ron-Nan Chien, Chun-Yen Lin, Chi-Chieh Yang, Gin-Ho Lo, Chi-Ming Tai, Chih-Wen Lin, Jia-Horng Kao, Chun-Jen Liu, Chen-Hua Liu, Sheng-Lei Yan, Ming-Jong Bair, Wei-Wen Su, Cheng-Hsin Chu, Chih-Jen Chen, Ching-Chu Lo, Pin-Nan Cheng, Yen-Cheng Chiu, Chia-Chi Wang, Jin-Shiung Cheng, Wei-Lun Tsai, Han-Chieh Lin, Yi-Hsiang Huang, Jee-Fu Huang, Chia-Yen Dai, Wan-Long Chuang, Ming-Lung Yu, Cheng-Yuan Peng: Risk stratification of hepatocellular carcinoma incidence using a fibrosis-4-based prediction model in patients with chronic hepatitis C receiving antiviral therapy: a nationwide real-world Taiwanese cohort study. Am J Cancer Res 2022;12(7):3164-3174. (Full text, PDF)
Hui Qiu, Qing-Gong Ma, Xue-Ting Chen, Xin Wen, Nie Zhang, Wan-Ming Liu, Ting-Ting Wang, Long-Zhen Zhang: Different classes of antibiotics exhibit disparate negative impacts on the therapeutic efficacy of immune checkpoint inhibitors in advanced non-small cell lung cancer patients. Am J Cancer Res 2022;12(7):3175-3184. (Full text, PDF)
Wen Li, Sheng Yu, Xu Duan, Senbang Yao, Lingxue Tang, Huaidong Cheng: COMT rs737865 mediates chemobrain in breast cancer patients with various levels of Ki-67. Am J Cancer Res 2022;12(7):3185-3197. (Full text, PDF)
Gukjin Lee, Kyungdo Han, Seong-Su Lee: Different effect of obesity and metabolic syndrome on prostate cancer by age group. Am J Cancer Res 2022;12(7):3198-3207. (Full text, PDF)
Xiao-Dong Mao, Xiao Wei, Tao Xu, Tai-Ping Li, Kang-Sheng Liu: Research progress in breast cancer stem cells: characterization and future perspectives. Am J Cancer Res 2022;12(7):3208-3222. (Full text, PDF)
Santosh Lamichhane, Ji-Su Mo, Grinsun Sharma, Sun-Myoung Joung, Soo-Cheon Chae: MIR133A regulates cell proliferation, migration, and apoptosis by targeting SOX9 in human colorectal cancer cells. Am J Cancer Res 2022;12(7):3223-3241. (Full text, PDF, Table S2)
Wenqing Chen, Zhu Zhang, Ken Kin-Lam Yung, Joshua Ka-Shun Ko: MUC1 is responsible for the pro-metastatic potential of calycosin in pancreatic ductal adenocarcinoma. Am J Cancer Res 2022;12(7):3242-3258. (Full text, PDF)
Yu Zhu, Tian Yu, Ju Huang, Xitao Ma, Tao Shen, Annuo Li, Rensong Yue: Development and validation of prognostic m6A-related lncRNA and mRNA model in thyroid cancer. Am J Cancer Res 2022;12(7):3259-3279. (Full text, PDF)
Tadeusz Kubicki, Kinga Bednarek, Magdalena Kostrzewska-Poczekaj, Magdalena Luczak, Krzysztof Lewandowski, Lidia Gil, Malgorzata Jarmuz-Szymczak, Dominik Dytfeld: Bortezomib- and carfilzomib-resistant myeloma cells show increased activity of all three arms of the unfolded protein response. Am J Cancer Res 2022;12(7):3280-3293. (Full text, PDF)
Ignacio Escobar-Munguía, Ricardo Berea-Baltierra, Ángel Morales-González, Eduardo Madrigal-Santillán, Liliana Anguiano-Robledo, José A Morales-González: Prognostic impact of the preoperatory neutrophil/lymphocyte index on early surgical complications of patients with colorectal cancer. Am J Cancer Res 2022;12(7):3294-3302. (Full text, PDF)
Xiaoxue Xi, Tianyue Cao, Yonghong Qian, Huiling Wang, Songwen Ju, Youguo Chen, Ting Chen, Jian Yang, Biaoquan Liang, Shunyu Hou: CDC20 is a novel biomarker for improved clinical predictions in epithelial ovarian cancer. Am J Cancer Res 2022;12(7):3303-3317. (Full text, PDF)
Jinan Guo, Chenhui Zhao, Xinzhou Zhang, Zhong Wan, Tingting Chen, Jiashun Miao, Jinping Cai, Wenchuan Xie, Hao Chen, Mengli Huang, Xiaochen Zhao, Wei Wei, Qi Shen: A novel 8-gene panel for prediction of early biochemical recurrence in patients with prostate cancer after radical prostatectomy. Am J Cancer Res 2022;12(7):3318-3332. (Full text, PDF)
Hsiao-Fan Chen, Po-Ren Hsueh, Yen-Yi Liu, Yeh Chen, Sui-Yuan Chang, Wei-Jan Wang, Chen-Shiou Wu, Ya-Min Tsai, Yu-Shu Liu, Wen-Chi Su, Yu-Chi Chou, Mien-Chie Hung: Disulfiram blocked cell entry of SARS-CoV-2 via inhibiting the interaction of spike protein and ACE2. Am J Cancer Res 2022;12(7):3333-3346. (Full text, PDF)
Lorenzo Fornaro, Gianna Musettini, Paola Orlandi, Irene Pecora, Caterina Vivaldi, Marta Banchi, Francesca Salani, Elisabetta Fini, Valentina Massa, Silvia Catanese, Federico Cucchiara, Monica Lencioni, Gianluca Masi, Enrico Vasile, Guido Bocci: Early increase of plasma soluble VEGFR-2 is associated with clinical benefit from second-line treatment of paclitaxel and ramucirumab in advanced gastric cancer. Am J Cancer Res 2022;12(7):3347-3356. (Full text, PDF)
Jingyi Chen, Fangxin Zhao, Hongxin Yang, Jianxun Wen, Ying Tang, Fang Wan, Xuan Zhang, Jianqiang Wu: Gentian violet induces apoptosis and ferroptosis via modulating p53 and MDM2 in hepatocellular carcinoma. Am J Cancer Res 2022;12(7):3357-3372. (Full text, PDF)
Myoung Woo Lee, Dae Seong Kim, Ji Eun Eom, Ji Won Lee, Ki Woong Sung, Hong Hoe Koo, Young Bin Hong, Keon Hee Yoo: Dual role of ERK2/NF-κB signaling in TRAIL sensitivity. Am J Cancer Res 2022;12(7):3373-3389. (Full text, PDF)
Jian-Hua Hong, Sung-Tzu Liang, Alexander Sheng-Shin Wang, Chia-Ming Yeh, Hsiang-Po Huang, Chia-Dong Sun, Zong-Han Zhang, Shih-Yu Lu, Yen-Hsiang Chao, Chung-Hsin Chen, Yeong-Shiau Pu: LMNB1, a potential marker for early prostate cancer progression. Am J Cancer Res 2022;12(7):3390-3404. (Full text, PDF)
Shuang-Yan Xie, Ding-Bo Shi, Yi Ouyang, Fei Lin, Xiao-Yu Chen, Tong-Chao Jiang, Wen Xia, Ling Guo, Huan-Xin Lin: SHMT2 promotes tumor growth through VEGF and MAPK signaling pathway in breast cancer. Am J Cancer Res 2022;12(7):3405-3421. (Full text, PDF)
Abigail Schoeller, Keshav Karki, Arul Jayaraman, Robert S Chapkin, Stephen Safe: Short chain fatty acids exhibit selective estrogen receptor downregulator (SERD) activity in breast cancer. Am J Cancer Res 2022;12(7):3422-3436. (Full text, PDF)
Gwan Hee Han, Hee Yun, Julie Kim, Joon-Yong Chung, Jae-Hoon Kim, Hanbyoul Cho: Overexpression of glucocorticoid receptor promotes the poor progression and induces cisplatin resistance through p38 MAP kinase in cervical cancer patients. Am J Cancer Res 2022;12(7):3437-3454. (Full text, PDF)
Ting Zhang, Xu Yang, Xiaobo Yang, Kanglian Zheng, Yanyu Wang, Yunchao Wang, Xinting Sang, Xin Lu, Yiyao Xu, Xiaodong Wang, Haitao Zhao: Different interventional time of hepatic arterial infusion with PD-1 inhibitor for advanced biliary tract cancer: a multicenter retrospective study. Am J Cancer Res 2022;12(7):3455-3463. (Full text, PDF)
Pan Jiang, Lianghao Mao, Xuan Lei, Chunshan Luo, Yiming Zhang, Xinyu Zhong, Zhenyu Yin, Xiaofeng Xu, Dapeng Li, Qiping Zheng: miR-1297 inhibits osteosarcoma cell proliferation and growth by targeting CCND2. Am J Cancer Res 2022;12(7):3464-3478. (Full text, PDF)
Peng Chen, Bing Liu, Bo Wei, Shujuan Yu: The clinicopathological features and treatments of odontogenic keratocysts. Am J Cancer Res 2022;12(7):3479-3485. (Full text, PDF)
Chao Dong, Yin Chen, Jing Ma, Runxiang Yang, Hongjian Li, Rong Liu, Dingyun You, Chunxiang Luo, Heng Li, Siyuan Yang, Kunbin Ke, Marie Chia-mi Lin, Ceshi Chen: Econazole nitrate reversed the resistance of breast cancer cells to Adriamycin through inhibiting the PI3K/AKT signaling pathway: Am J Cancer Res. 2020; 10(1): 263-274. Am J Cancer Res 2022;12(7):3486-3490. (Full text, PDF)
Shaomin Shi, Chongyang Li, Yanli Zhang, Chaowei Deng, Mengqin Tan, Guangzhao Pan, Juan Du, Yacong Ji, Qian Li, Hanghua Liang, Wei Liu, Leiyang Guo, Gaichao Zhao, Yaling Liu, Hongjuan Cui: Lycorine hydrochloride inhibits melanoma cell proliferation, migration and invasion via down-regulating p21Cip1/WAF1: Am J Cancer Res. 2021; 11(4): 1391-1409. Am J Cancer Res 2022;12(7):3491-3494. (Full text, PDF)
