Jian Zhao, Bin Liu, Ning Liu, Benxia Zhang, Xia He, Qizhi Ma, Yongsheng Wang: The role of angiogenesis in malignant pleural effusion: from basic research to clinical application. Am J Cancer Res 2022;12(11):4879-4891. (Full text, PDF)
Dehua Zhao, Xiaoqing Long, Hongying Fan, Jisheng Wang: Effects of hepatic or renal impairment on the pharmacokinetics of immune checkpoint inhibitors. Am J Cancer Res 2022;12(11):4892-4903. (Full text, PDF)
Qiang Guo, Xiao-Li Liu, Ni Jiang, Wen-Jun Zhang, Shao-Wen Guo, Heng Yang, Yan-Mei Ji, Jun Zhou, Jia-Long Guo, Jun Zhang, Hua-Song Liu: Decreased APOC1 expression inhibited cancer progression and was associated with better prognosis and immune microenvironment in esophageal cancer. Am J Cancer Res 2022;12(11):4904-4929. (Full text, PDF, Table S1)
Shan-Mei Chen, Jun-Nan Feng, Chuan-Ke Zhao, Li-Cheng Yao, Li-Xin Wang, Lin Meng, Shao-Qing Cai, Cai-Yun Liu, Li-Ke Qu, Yan-Xing Jia, Cheng-Chao Shou: A multi-targeting natural product, aiphanol, inhibits tumor growth and metastasis. Am J Cancer Res 2022;12(11):4930-4953. (Full text, PDF)
Bixi Zhang, Peng Liu, Yanchun Li, Qing Hu, Huan Li, Xiaoyang Pang, Hao Wu: Multi-omics analysis of kinesin family member 2C in human tumors: novel prognostic biomarker and tumor microenvironment regulator. Am J Cancer Res 2022;12(11):4954-4976. (Full text, PDF)
Sanjit Roy, Tijana Dukic, Binny Bhandary, Kevin J Tu, Jason Molitoris, Young H Ko, Hem D Shukla: 3-Bromopyruvate inhibits pancreatic tumor growth by stalling glycolysis, and dismantling mitochondria in a syngeneic mouse model. Am J Cancer Res 2022;12(11):4977-4987. (Full text, PDF)
Minghui Zhang, Bowen Yang, Lingyun Zhang, Xiaoyu Guo, Guangwei Zhang, Xiaofang Che, Ce Li, Kezuo Hou, Xiaojie Zhang, Jinglei Qu, Ti Wen, Xiujuan Qu: TRIM27 is an adverse prognostic biomarker and associated with immune and molecular profiles in right-sided colon cancer. Am J Cancer Res 2022;12(11):4988-5003. (Full text, PDF)
Feng Qian, Haoyue Xu, Yongkang Zhang, Linfeng Li, Rutong Yu: Methionine deprivation inhibits glioma growth through downregulation of CTSL. Am J Cancer Res 2022;12(11):5004-5018. (Full text, PDF)
Ichiro Yajima, Akira Tazaki, Nobutaka Ohgami, Masashi Kato: Calcitriol inhibits arsenic-promoted tumorigenesis through regulation of arsenic-uptake in a human keratinocyte cell line. Am J Cancer Res 2022;12(11):5019-5028. (Full text, PDF)
Yiyang Li, Wei Zhou, Long Li, John W Li, Tianyue Li, Cheng Huang, Vanessa J Lazaro-Camp, Tamar Kavlashvili, Yuping Zhang, Henry Reyes, Yujun Li, Donghai Dai, William Zhu, Xiangbing Meng, Kimberly K Leslie, Shujie Yang: Enhancing progestin therapy via HDAC inhibitors in endometrial cancer. Am J Cancer Res 2022;12(11):5029-5048. (Full text, PDF)
Ching-Yun Hsieh, Wei-Chao Chang, Ching-Chan Lin, Jong-Hang Chen, Chen-Yuan Lin, Chia-Hua Liu, Chen Lin, Mien-Chie Hung: Combination treatment of arsenic trioxide and osimertinib in recurrent and metastatic head and neck squamous cell carcinoma. Am J Cancer Res 2022;12(11):5049-5061. (Full text, PDF, Table S2)
Nai-Jung Chiang, Yan-Shen Shan, Chung-Pin Li, Shih-Hung Yang, Yung-Yeh Su, Sz-Chi Chiu, Li-Yuan Bai, Shih-Chang Chuang, De-Chuan Chan, Chia-Jui Yen, Cheng-Ming Peng, Tai-Jan Chiu, Yen-Yang Chen, Jen-Shi Chen, Wen-Chi Chou: The impact of starting dose with or without subsequent dose escalation of liposomal irinotecan on treatment outcomes in patients with metastatic pancreatic ductal adenocarcinoma. Am J Cancer Res 2022;12(11):5062-5073. (Full text, PDF)
Yanlin Li, Tiantian Wu, Ziluo Peng, Xianyan Tian, Qian Dai, Miao Chen, Jun Zhu, Song Xia, Aiqin Sun, Wannian Yang, Qiong Lin: ETS1 is a prognostic biomarker of triple-negative breast cancer and promotes the triple-negative breast cancer progression through the YAP signaling. Am J Cancer Res 2022;12(11):5074-5084. (Full text, PDF)
Keng-Hao Liu, Yu-Shin Hung, Shu-Hui Lee, Cheng-Chou Lai, Shu-Chen Chen, Wei-Ling Kao, Hui-Wen Cheng, Mei-Hui Hsu, Chun-Yi Tsai, Shun-Wen Hsueh, Chia-Yen Hung, Yung-Chang Lin, Wen-Chi Chou: External validation of a risk model for survival prediction in older patients with cancer undergoing elective abdominal surgery: a prospective cohort study. Am J Cancer Res 2022;12(11):5085-5094. (Full text, PDF)
Shen Yan, Yucun Liu, Guowei Chen, Yanpeng Yang: Defining early recurrence of locally recurrent rectal cancer. Am J Cancer Res 2022;12(11):5095-5104. (Full text, PDF)
Ganghui Ye, Jie Wang, Weili Yang, Jinyun Li, Meng Ye, Xiaofeng Jin: The roles of KLHL family members in human cancers. Am J Cancer Res 2022;12(11):5105-5139. (Full text, PDF)
Bashir Lawal, Yu-Cheng Kuo, Harshita Khedkar, Ntlotlang Mokgautsi, Maryam Rachmawati Sumitra, Alexander TH Wu, Hsu-Shan Huang: Deciphering the immuno-pathological role of FLT, and evaluation of a novel dual inhibitor of topoisomerases and mutant-FLT3 for treating leukemia. Am J Cancer Res 2022;12(11):5140-5159. (Full text, PDF)
Kai Lei, Binghua Tan, Ruihao Liang, Yingcheng Lyu, Kexi Wang, Wenjian Wang, Kefeng Wang, Xueting Hu, Duoguang Wu, Huayue Lin, Minghui Wang: Development and clinical validation of a necroptosis-related gene signature for prediction of prognosis and tumor immunity in lung adenocarcinoma. Am J Cancer Res 2022;12(11):5160-5182. (Full text, PDF)
Lingyu Zhao, Xiaofei Wang, Juan Yang, Qiuyu Jiang, Jing Zhang, Feng Wu, Lei Ni, Dongdong Tong, Chen Huang: MECP2 promotes the migration and invasion of gastric cancer cells by modulating the Notch1/c-Myc/mTOR signaling pathways by suppressing FBXW7 transcription. Am J Cancer Res 2022;12(11):5183-5204. (Full text, PDF)
Bin Zhou, Ying Huang, Qian Feng, Hengqing Zhu, Zheng Xu, Leifeng Chen, Xiaogang Peng, Wenlong Yang, Debin Xu, Yumin Qiu: TRIM16 promotes aerobic glycolysis and pancreatic cancer metastasis by modulating the NIK-SIX1 axis in a ligase-independent manner. Am J Cancer Res 2022;12(11):5205-5225. (Full text, PDF)
Zhe Hu, Jinlan Meng, Hongbing Cai, Na Ma, Xiujie Gao, Xiaojuan Li, Yan Xu: KIF3A inhibits nasopharyngeal carcinoma proliferation, migration and invasion by interacting with β-catenin to suppress its nuclear accumulation. Am J Cancer Res 2022;12(11):5226-5240. (Full text, PDF)
Rong Xu, Xin Wu, Ashuai Du, Qiangqiang Zhao, He Huang: Identification of cuproptosis-related long non-coding ribonucleic acid signature as a novel prognosis model for colon cancer. Am J Cancer Res 2022;12(11):5241-5254. (Full text, PDF)
Ben-Ling Xu, Xiao-Ming Wang, Guang-Yu Chen, Peng Yuan, Lu Han, Peng Qin, Tie-Peng Li, Hong-Qin You, Cheng-Juan Zhang, Xiao-Min Fu, Long Yuan, Zi-Bing Wang, Quan-Li Gao: In vivo growth of subclones derived from Lewis lung carcinoma is determined by the tumor microenvironment. Am J Cancer Res 2022;12(11):5255-5270. (Full text, PDF)
Rongrong Wu, Irene Yu, Yoshihisa Tokumaru, Mariko Asaoka, Masanori Oshi, Li Yan, Shujiro Okuda, Takashi Ishikawa, Kazuaki Takabe: Elevated bile acid metabolism and microbiome are associated with suppressed cell proliferation and better survival in breast cancer. Am J Cancer Res 2022;12(11):5271-5285. (Full text, PDF)
Yuzhu Chen, Yazhi Qian, Wei Huang, Yi Zhang, Mo Wu, Yinlong Cheng, Nan Yang, Yanyong Liu: Chronic stress promotes tumor immune evasion via the suppression of MHC-I expression and the upregulation of PD-L1. Am J Cancer Res 2022;12(11):5286-5299. (Full text, PDF)
Peng Liu, Feng Jiao, Zhenghua Zhang, Feilong Zhao, Jinping Cai, Shiqing Chen, Tao Fu, Min Li: Identification of BIK as an unfavorable prognostic marker and novel therapeutic target in microsatellite stable colorectal cancer harboring KRAS mutations. Am J Cancer Res 2022;12(11):5300-5314. (Full text, PDF)
Jinmei Li, Yue Xu, Hua Liu, Bin Guo, Xiaolan Guo, Yushan Li, Xingliang Jiang, Qiang Wang: Construction and validation of NSMC-ASIL, a predictive model for risk assessment of malignant hepatic nodules. Am J Cancer Res 2022;12(11):5315-5324. (Full text, PDF)
Chih-Ming Ho, Ting-Lin Yen, Tsai-Yen Chien, Shih-Hung Huang: Distinct promotor methylation at tumor suppressive genes in ovarian cancer stromal progenitor cells and ovarian cancer and its clinical implication. Am J Cancer Res 2022;12(11):5325-5341. (Full text, PDF)
Ching-Fu Chang, Ming-Han Yang, Jih-Hsiang Lee, Shyang-Rong Shih, Chia-Hung Lin, Chiao-Ping Chen, Chiao-En Wu, Jin-Ying Lu: The impact of BRAF targeting agents in advanced anaplastic thyroid cancer: a multi-institutional retrospective study in Taiwan. Am J Cancer Res 2022;12(11):5342-5350. (Full text, PDF)
